First-base umpire Vic Carapazza called Guyer safe, and Angels manager Mike Scioscia eventually came out of the dugout to challenge the play.
After a 1-minute, 25-second review, the ruling on the field stood. Guyer remained at first and the Angels lost their challenge.
Angels reliever Michael Roth then retired Evan Longoria on a forceout to short to end the inning with no damage.
Being out of challenges didn't stop Scioscia from requesting a review on a play at the plate in the ninth inning with the Rays ahead, 10-3.
Right fielder Kevin Kiermaier, on as a defensive replacement, gunned down Cron at home on Chris Iannetta's single to right, but crew chief Larry Vanover agreed to review the play for a collision violation on Rays catcher Curt Casali.
After a 1-minute, 26-second review, the ruling on the field was confirmed -- there was no collision violation, and Cron was out.
David Adler is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.