Cobb's start marked the first time in Major League history that a pitcher struck out 13 in an appearance lasting fewer than five innings.
And his third inning marked the first time since Major League inning records are first available that a team scored a run in an inning in which every batter struck out (three or more batters). The Padres sent four batters to the plate and all four struck out -- but they still managed to score a run.
Here's what happened:
Cobb struck out Will Venable to start the third, but he uncorked a wild pitch that rolled to the backstop for strike three. That allowed Venable to reach first. Venable then stole second on the same pitch that saw Chase Headley become Cobb's second victim.
Venable stole third shortly before Carlos Quentin became Cobb's third strikeout of the inning.
Despite Cobb's bad luck, he appeared close to escaping the inning unscathed. And he would have had he not balked, which allowed Venable to score the Padres' third run.
Yonder Alonso then struck out swinging to give Cobb four strikeouts for the inning -- and nine through three innings of work.
"I was mad at myself for half that inning," Cobb said. "I gave up two stolen bases, which I've been working hard on not to do. After that balk, I don't know if I've been any angrier when I've been pitching."
Bill Chastain is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.