In two rehab appearances with Triple-A Durham, the 34-year-old went 3-for-8 with a pair of homers, four RBIs and three runs.
"I went down to Durham to see some pitching, and I feel like I'm ready," Scott said.
Hitting cleanup on Thursday, Scott, Tampa Bay's leader in RBIs (35), should give the club's offense a boost.
"He's been swinging the bat well on his little rehab stint," Rays manager Joe Maddon said. "He was swinging the bat well working out, we'll see how it works."
Maddon added he isn't sure whether Scott is able to take on an everyday role for the team, but Scott will be evaluated after Thursday's game.
Entering Thursday's game, Scott is batting .220 on the season with nine long balls, but he struggled in his 11 games before landing on the disabled list when he went 5-for-37 during the stretch.
To make room on the roster, righty Chris Archer was sent down to Durham after making a pair of starts, allowing four earned runs in 11 2/3 innings of work.
"He should have been pleased with what he did here," Maddon said of Archer. "He definitely learned how much he belongs and that he can pitch in the big leagues so that's the first positive."