Rays manager Joe Maddon said the cramping started during Navarro's at-bat in the fifth inning and after assuming the field for the top of the sixth inning the backstop's legs were still sore.
"I felt a little tightness and I'd rather come out before making it worse," Navarro said through a message to Rays spokesperson Chris Costello.
Scheduled to bat with two outs and two runners on base, backup catcher Shawn Riggans was inserted as a pinch-hitter instead. After Riggans struck out, he assumed the backstop duties for the Rays in Tuesday's series opener.
"It just happened so fast with Navi and the leg," Maddon said of the decision to insert Riggans to pinch-hit. The Rays scored their only two runs in the sixth inning and Maddon was debating whether or not to insert switch-hitting Ben Zobrist to pinch-hit instead, and adding Riggans as a defensive replacement the following inning.
Navarro was receiving treatment after the game and was unsure -- as was Maddon -- whether he would be available for Wednesday's contest.
"It's a day-to-day thing," Navarro said, adding that he planned on arriving to Tropicana Field early for further examination.
Brittany Ghiroli is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.