The throw that hit Pierzynski in the back came in the third inning of the White Sox 4-3 win over the Rays.
"It was a pretty standard 0-0 pitch," Pierzynski said about the incident.
In the fourth, a pitch from White Sox pitcher Jose Quintana went well behind Zobrist, prompting home-plate umpire Mark Wegner to eject Quintana and White Sox manager Robin Ventura for the first time in his managerial career.
"I'd never seen anything like it," Ventura said. "I don't know how to explain it. ... I was shocked."
Rays manager Joe Maddon said "it's pretty obvious" when a pitcher throws behind a player.
"Pierzynski slid awkwardly into second base," Maddon said. "He got hit with a pitch today, and then they threw behind us. There was nothing from me to any of our players today. Nothing."
Quintana had been pitching well on Wednesday, allowing only one run on one hit -- a solo homer by Luke Scott -- while striking out two in 3 2/3 innings. Right-hander Nate Jones came on in relief of Quintana.